The Breakthrough 25 Gala: Inaugural Edition
Celebrating 25 Years of Bioscience Innovation.
Growing a Vibrant St. Louis Economy for Generations to Come.
Join Us on August 27, 2026
The Ritz Carlton
Be Part of the St. Louis Renaissance
Since 2001, we have been driven by a bold vision for St. Louis: re-establishing the region once again as a place of great exploration and discovery. Together with our coalition of partners, we have shaped St. Louis into a leading hub for ag tech and health innovation – two of the region’s greatest competitive strengths.
Today, our goal to create a local bioscience-driven economy for St. Louis is real. The economic impact is real with billions of dollars in local GDP, thousands of jobs, and hundreds of startups created.
But there is so much more opportunity.
Be Part of What’s Next
We invite you to join us for a celebration of progress and possibility. The inaugural breakthrough gala brings together leaders from across the region with a singular focus: investing in the future of our growing bioscience economy and building momentum for what’s next.
Your support makes possible:
- Breakthrough innovations in health and agriculture with real-world impact
- The discovery and creation of high-impact bioscience companies based in St. Louis
- A stronger, local innovation local economy with future-focused, high-paying jobs
- A renaissance of St. Louis that instills pride locally and drives our reputation and standing nationally and globally
Gala Leadership
Honorary Chairs
- John and Anne McDonnell
Co-Chairs
- Valerie Bell and Kelvin Westbrook
- Hazel and Arnold Donald
- Laura and Michael Ellenhorn
- Jane and Dave Peacock
Host Committee
- Mark Wrighton and Risa Zwerling
- Louise and Steve Epner
- Ruth E. Kim and David T. Hamilton
- Wes Jones and Nancy Ylvisaker
- Lyn and Ron Kitchens
- Brian Salmo
- Ellen and Dennis Riggs
- Derek Rapp
- Michelle and Scott Harris
- Marc Schrieber
- Don Suggs
- Barry T. Cervantes
- Brad Dean
- Dr. Jerry Dwyer and Tina R. Sappington
- Stuart Bradley
Thank You to Our Gala Sponsors
Premier
Michael W. & Quirsis V. Riney
Diamond
John & Anne McDonnell
Gold
Bob & Signa Hermann Foundation, Mission Video Sponsor
Mark Wrighton & Risa Zwerling
Silver
Laura & Michael Ellenhorn
Bronze
John & Judith McCarter
Emily Pulitzer
Wes Jones & Nancy Ylvisaker
Non-Profit Ecosystem Partner